PEAK HUMAN LABS Podcast

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Join Dr Sanjeev Goel, as we explore the cutting edges of medical knowledge to ”BE PEAK NOW”

Episodes

Tuesday Nov 12, 2024

Secrets of the Forgotten Mushroom”

Tuesday Nov 12, 2024

Could the answer to anxiety and sleep issues be found in a mushroom? Amanita muscaria, a unique and legal psychedelic, might be the breakthrough the mental health world has been waiting for. But what makes this mushroom so special?

In this episode of the Peak Human Labs Podcast, Dr. Goel sits down with serial entrepreneur Alex Wolfe to explore the promising mental health benefits of Amanita muscaria, a legal psychoactive mushroom known for its calming and mood-enhancing properties. Alex, founder of Eons, shares how his company is at the forefront of microdosing technology, using muscimol—a unique compound that interacts with the brain's GABA receptors to promote relaxation and mental clarity. EON's innovative products, including a sleep aid and the new "Social Dose" (a safe, legal alternative to alcohol), are crafted to support mental wellness naturally and effectively.

The conversation also highlights Eon's dedication to rigorous research, with an upcoming study involving veterans to deepen understanding of Amanita’s therapeutic effects. Alex and Dr. Goel inspire listeners to consider natural options for mental wellness rooted in tradition and science.

Try It Yourself: Ready to explore the benefits of Amanita muscaria? Head over to the Eons http://www.eons.com/ and use our special discount code: “peakhuman”.

Key Takeaways

Introduction to Amanita muscaria and its psychoactive properties.
The importance of responsible psychedelic use for mental health.
The innovative product was developed by Eons for legal psychedelic microdosing.
The active ingredient muscimol and its effects on the brain.
Comparison of muscimol's calming effects to traditional medications targeting GABA receptors.
User experience and benefits of Amanita muscaria microdosing, including improved clarity and anxiety relief.
Safety measures and recommended dosage for the product.
Innovative delivery method using patented bioavailability technology for rapid absorption.
Cultural significance and historical context of Amanita muscaria in various societies.
Future product developments and the potential impact on mental health solutions.

In This Episode:

[00:37]Introduction to Alex Wolfe
[01:05] Product reveal
[01:34] Alex's background
[01:54] Psychedelics and mental health
[03:11] Types of mushrooms
[04:45] Introduction to muscimol
[05:15] Psychedelic effects explained
[06:59] User experience with Muscimol
[08:18] Research on micro-dosing
[09:38] Amanita muscaria overview
[10:03] Safety of amanita muscaria
[12:57] Dosage discussion
[14:05] Delivery method explained
[16:21] Recommended usage
[17:42] Long-term effects of use
[18:45] Cultural significance of amanita muscaria
[21:09] Product availability and pricing
[21:57] Introduction to mental health solutions
[22:16] Sleep product development
[22:25] Addressing anxiety
[22:49] Upcoming product: Social Dose
[23:29] Feedback and experiences
[24:01] Veteran study launch
[24:26] Dr. Goel's experience with sleep product
[25:10] Lifestyle supplement discussion
[25:29] Discount code announcement
[25:51] Conclusion and summary

Resources and Links

Peak Human Labs

Dr. Sanjeev Goel

https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca

Alex Wolfe

Mentioned Book

Microdosing with Amanita Muscaria

Wednesday Oct 02, 2024

Reversing Aging with Hyperbaric Oxygen

Wednesday Oct 02, 2024

Hyperbaric Oxygen Therapy (HBOT) has increasingly gained recognition for its myriad health benefits. Many think of HBOT as a specialized medical treatment that involves breathing pure oxygen in a pressurized environment. This therapy, often performed in a hyperbaric chamber, significantly raises the oxygen levels in blood and tissues, offering a range of therapeutic benefits.

In this episode of the Peak Human Labs Podcast, Dr. Sanjeev Goel sits down with Dr. Joseph Dituri, a retired Navy diver and expert in hyperbaric oxygen therapy. Dr. Dituri shares insights from his groundbreaking 100-day underwater experiment, which demonstrated remarkable health benefits, including reversing his biological age by 10 years. This conversation dives deep into the fascinating world of hyperbaric oxygen therapy, its impact on longevity, and how it can enhance physical and mental well-being.

Dr. Dituri discusses the profound effects of hyperbaric oxygen on increasing telomere length, reducing inflammation, and boosting stem cell proliferation. He also reflects on his time underwater and its impact on his sleep, energy levels, and overall health. Whether you're interested in cutting-edge longevity research or just curious about the future of medical science, this episode has something for everyone.

Key Takeaways

How hyperbaric oxygen therapy works
The potential for reversing aging
Impact of hyperbaric therapy on telomeres, inflammation, and stem cells
The connection between deep sleep and brain health
Longevity practices and healing from within

In This Episode:

00:00:00: Misconceptions about hyperbaric oxygen therapy
00:01:24: Introduction of Dr. Joseph Daturi
00:01:58: Overview of hyperbaric oxygen therapy and undersea stay
00:03:01: Dr. Daturi's background and involvement in hyperbaric research
00:04:28: Discovery of a potential Alzheimer's treatment
00:05:00: Reasons behind the 100-day undersea stay
00:06:39: Telomere lengthening through hyperbaric therapy
00:08:57: Impact of hyperbaric therapy on inflammation
00:09:43: Improved sleep and other biological effects during the undersea stay
00:14:33: Blood parameters and cortisol changes
00:16:00: Post-stay health changes and lasting effects
00:17:22: Implications and future of hyperbaric oxygen therapy
00:17:57: Overview of the problem with current medical treatments
00:18:32: Discussion on diseases related to inflammation
00:19:29: Feasibility of living in the ocean
00:20:07: Shift from traditional medical care to holistic approaches
00:21:21: Known benefits of hyperbaric therapy
00:22:02: Personal use of hyperbaric chambers
00:23:00: Oxygen therapy's mechanisms and health benefits
00:24:03: Plans and research on muscle size increase in zero gravity
00:25:23: Benefits of traveling in a hyperbaric state for space missions
00:26:28: Application to NASA and potential impact on space travel
00:27:02: Episode conclusion and summary with Dr. Joseph Daturi

Our Guest

As president of the Undersea Oxygen Clinic, Dr. Dituri has applied his Ph.D. in Biomedical Engineering to the development of a breakthrough treatment for healing Traumatic Brain Injury (TBI), Chronic Traumatic Encephalopathy (CTE), and the related symptoms of PTSD, depression, and long-term mental and physical impairments.

Joseph Dituri is an American biomedical researcher and former Naval Commander. Also known as Dr. Deep Sea his research includes life support equipment design, high carbon dioxide environments, hyperbaric medicine, hyperbaric medicine, and traumatic brain injury.

Resources and Links

Peak Human Labs

Dr. Sanjeev Goel

https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca

Dr. Joseph Dituri

Thursday Sep 26, 2024

Wimhof, Breath Cold and Stress

Thursday Sep 26, 2024

There is stress that heals and sustains high performance, and there is stress that breaks you down. Discover the key pathways of stress to live your best life! Get the book by visiting https://www.mattsoule.com/book

Stress can feel like an uninvited guest that overstays its welcome, impacting our health and performance in ways we often overlook. But what if you could transform that stress into a powerful tool for personal growth?

In this episode of the Peak Human Labs Podcast Dr. Goel sits down with Matt Soule, a U.S.-based author and expert in the Wim Hof Method, which focuses on managing stress. Matt opens up about his journey of overcoming childhood trauma through martial arts and how it led him to embrace the Wim Hof Method. This powerful approach combines breathing exercises, cold exposure, and a strong mindset to enhance well-being and tackle stress head-on.

Matt breaks down the method's key components, including energizing breaths that boost adrenaline, calming breaths for relaxation, and the importance of balanced breathing. He even shares a simple step-by-step breathing protocol that can help listeners experience benefits like improved oxygenation and mental clarity. Additionaly, he emphasizes the perks of cold exposure, which releases feel-good chemicals and builds resilience.

Matt highlights the science behind the method, showcasing its ability to regulate stress hormones and reduce inflammation. He encourages everyone to dedicate just a few minutes daily to these practices. By embracing the Wim Hof Method, you can manage stress effectively and improve your overall well-being. For those interested, Matt offers resources like workshops and a free membership to help you master stress! Let’s dive in!

Key Takeaways

Stress management techniques
The Wim Hof Method
Breathing exercises and their impact on stress
Personal journey of overcoming childhood trauma
Role of martial arts in stress relief
Physiological benefits of cold exposure
Importance of selecting beneficial stressors
Anecdotes illustrating the effectiveness of the Wim Hof Method
The relationship between health and high performance
Resources for further learning and practice in stress management techniques

In This Episode:

[00:48] Matt Soule’s background
[02:29] Martial arts as stress relief
[03:25] Transition to owning a martial arts school
[05:07] Injury and discovery of the Wim Hof method
[07:22] The importance of breath in healing
[08:39] Overview of the Wim Hof method
[10:02] Demonstration of breathing techniques
[12:09] The three parts of the breathing protocol
[13:09] Breath hold technique
[16:00] Completing a breathing round
[16:54] Daily practice recommendations
[17:29] Understanding the 30-40 breaths
[19:05] Chronic stress and breathing patterns
[20:58] Comparison with other breathing traditions
[21:07] Breathing techniques in the Wim Hof method
[23:19] Breath control and adaptability
[24:18] Scientific studies on Wim Hof method
[27:17] Rapid benefits of Wim Hof method
[30:35] Starting cold exposure practice
[34:15] Risks of cold exposure
[37:23] Contrast therapy with sauna and cold
[40:20] Adaptation to cold over time
[41:21] The benefits of cold exposure
[42:07] Introduction to Matt's books
[42:13] Stronger through stress
[43:12] Personal success story
[44:10] The stress paradox
[44:53] Choosing the right stress
[45:06] The necessity of stress
[45:41] Resources for learning

Our Guest

Matt Soule is a U.S.-based author, speaker, and professional instructor dedicated to helping individuals leverage stress for peak performance. His journey began with childhood exposure to domestic violence, motivating him to combat stress through martial arts and the Wim Hof Method, where he became one of the first certified instructors in the U.S. Over 15 years, Matt has taught over 10,000 people and trained more than 600 instructors globally. He’s the author of a book on mastering stress and is currently collaborating with Bradley Corporation on The Stress Paradox. Passionate about wellness, Matt leads workshops worldwide, impacting lives through innovative stress management strategies.

Resources and Links

Peak Human Labs

Dr. Sanjeev Goel

https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca

Matt Soule

Mentioned Books

Stronger Through Stress

The Stress Paradox

Unstressed

Wednesday Sep 18, 2024

Unlocking the Power of Nitric Oxide

Wednesday Sep 18, 2024

Click here for Nitric Oxide products https://n1o1.com/ and use “Peakhuman” as a coupon code for 10% off!

Did you know that a tiny molecule could have a monumental impact on your health and well-being? Nitric oxide (NO) might be the unsung hero in your body, influencing everything from blood flow and exercise performance to disease prevention and recovery.But what makes this molecule so powerful?

In this episode of the Peak Human Labs Podcast, Dr. Sanjeev Goel speaks with Dr. Nathan Bryan, a leading expert in nitric oxide physiology. They explore NO's crucial role in human health, including its impact on blood flow, circulation, and oxygen delivery. Dr. Bryan explains the two primary pathways of NO production: enzymatic synthesis from L-arginine and dietary nitrates converted by oral bacteria. They also discuss how diet, oral health, and medications like proton pump inhibitors influence NO levels. Additionally, Dr. Bryan introduces innovative NO supplementation strategies, highlighting their potential benefits for cardiovascular health and disease prevention.

Tune in to discover how this remarkable molecule could be the key to enhancing your health.

Key Takeaways

Importance of nitric oxide (NO) in human health
Mechanisms of nitric oxide production in the body
Pathways of nitric oxide synthesis, including the role of nitric oxide synthase (NOS) enzymes
Impact of diet and oral bacteria on nitric oxide levels
Implications of nitric oxide deficiency on various health conditions
Effects of dietary choices, particularly nitrates from vegetables, on nitric oxide production
Relationship between endothelial function and nitric oxide
Nitric oxide supplementation strategies and their effectiveness
Pharmacokinetics of nitric oxide delivery methods
Potential therapeutic applications of nitric oxide in treating diseases like ischemic heart disease and Alzheimer’s disease

In This Episode:

[01:25] Dr. Bryan's background
[03:13] Significance of nitric oxide
[03:30] Misconceptions about nitric oxide
[06:29] Mechanisms of nitric oxide production
[08:20] Dietary influence on nitric oxide
[09:34] Impact of oral bacteria
[18:26] Antacids and nitric oxide deficiency
[21:40] Young people and nitric oxide deficiency
[22:55] Endothelial function and glycocalyx
[24:17] Nitric oxide supplements
[26:13] Introduction to nitric oxide
[26:51] Mechanism of action
[28:00] Restoring oral microbiome
[29:01] Saliva and nitric oxide production
[29:30] Dosage and frequency recommendations
[31:25] Timing for optimal effects
[32:22] Synergistic effects with medications
[33:40] Tolerance and nitric oxide depletion
[34:18] Details about Dr. Bryan's nitric oxide products and their benefits.
[40:09] Conclusion and resources to learn more about nitric oxide.

Our Guest

Dr. Nathan Bryan earned his B.S. in Biochemistry from the University of Texas at Austin and his M.D. from Louisiana State University School of Medicine, where he received the Dean’s Award for Excellence in Research. He completed post-doctoral training as a Kirschstein Fellow at Boston University's Whitaker Cardiovascular Institute. Recruited by Nobel Laureate Ferid Murad to the University of Texas Health Science Center at Houston, Dr. Bryan has pioneered nitric oxide research for 20 years, resulting in numerous patents and significant advancements in patient care. He is the Founder and CEO of Bryan Therapeutics, Inc., leading in nitric oxide-based therapies for various conditions.

Resources and Links

Peak Human Labs

Dr. Sanjeev Goel

https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca

Dr. Nathan Bryan

Tuesday Sep 17, 2024

Gaurav’s Life-Changing Health Journey With Peak Human - How He Lost 150 Pounds!

Tuesday Sep 17, 2024

In this inspiring episode, Dr. Goel sits down with Gaurav, who has achieved a remarkable weight loss of 150 pounds through his dedicated journey with Peak Human. Gaurav opens up about his transformative experience, the challenges he faced, and the incredible milestones he’s reached along the way. His story is a powerful testament to the impact of personalized health strategies and determination. Whether you're looking for motivation or practical tips on your own health journey, this episode is a must-watch! Listen to the full podcast now and be inspired by Gaurav’s incredible journey. You won’t want to miss his valuable insights and tips for success!

Friday Sep 06, 2024

How far till Longevity Escape Velocity?

Friday Sep 06, 2024

They say aging is just a part of life, but have you ever wondered if it really has to be? What if getting older isn’t just something we accept but something we could actually treat?

In this riveting episode of Peak Human Labs Podcast, Dr. Sanjeev Goel, sits down with Dr. Aubrey de Grey, a trailblazing biomedical gerontologist and Chief Science Officer of the SENS Research Foundation. They dive deep into the revolutionary idea of treating aging as a medical condition. They explore how damage accumulates in our bodies over time and discuss the groundbreaking medical advancements that could extend our healthy lifespans. Dr. de Grey sheds light on the crucial need for investing in underfunded research and shares insights into the future of longevity science. Tune in and envision a future where health and longevity are not just aspirations but achievable realities!

Click HERE to sign in for Dublin Longevity Declaration.

Key Takeaways

Aging as a medical condition versus a natural process
Mechanisms of damage accumulation in the body
Concept of "longevity escape velocity"
Role of epigenetic changes in aging
Importance of comprehensive interventions targeting different types of damage
Current state of therapies for extending human lifespan
Economic implications of aging therapies and preventative medicine
Research on retroviruses and chronic infections in relation to aging
Innovative therapies such as hyperbaric oxygen therapy and therapeutic blood exchange
The significance of personalized health approaches and the microbiome's impact on longevity

In This Episode:

[00:00:00] Introduction to longevity research
[00:00:51] Guest introduction
[00:01:17] Personal connection
[00:02:04] Dr. de Grey's background
[00:03:14] Early research stages
[00:04:05] Understanding aging as a machine
[00:05:22] Accumulated damage mechanism
[00:06:15] Comprehensive medical control
[00:07:13] Categories of damage
[00:07:55] Wear and tear concept
[00:09:20] Epigenetic changes discussion
[00:11:31] Partial reprogramming concept
[00:13:30] Addressing multiple mechanisms
[00:14:31] Longevity escape velocity
[00:15:43] Initial pushback on longevity ideas
[00:17:51] Positive outlook on aging research
[00:19:51] The future of longevity research
[00:20:54] Funding disparities in research
[00:21:10] Business models in longevity research
[00:21:58] Combining existing therapies
[00:23:47] Current longevity therapies
[00:24:56] Caloric restriction vs. drugs
[00:25:36] Dublin Longevity Declaration
[00:28:09] Anticipating longevity breakthroughs
[00:29:12] Access to longevity therapies
[00:30:58] Epigenetic clocks and age reversal
[00:32:24] Retroviruses and aging
[00:34:56] Persistent viral infections
[00:37:24] Hyperbaric oxygen therapy
[00:39:37] Discussion on active ingredients
[00:40:41] Bone marrow transplant experimentation
[00:42:09] Health benefits of bone marrow transplants
[00:43:55] Advice for maximizing healthy lifespan
[00:45:01] Microbiome and longevity

Our Guest

Dr. Aubrey de Grey is a biomedical gerontologist and founder of the LEV Foundation, focused on repairing aging-related cellular damage. Based in Silicon Valley, he earned his BA in computer science and Ph.D. in biology from the University of Cambridge. His research targets the characterization and repair of aging damage. A Fellow of the Gerontological Society of America and the American Aging Association, he advises numerous journals and organizations and is a sought-after speaker at scientific and public events.

Resources and Links

Peak Human Labs

Dr. Sanjeev Goel

https://www.linkedin.com/in/sanjeevgoelmd/?originalSubdomain=ca

Dr Aubrey de Grey

Friday Aug 02, 2024

C15:0 A Remarkable Fatty Acid | With Fatty15 Co-Founder Dr.Steph

Friday Aug 02, 2024

Dr Goel interviews Dr Steph about this remarkable C:15 fatty acid called Fatty 15

To get your 20% discount on Fatty15 click here

In this fascinating conversation with Dr. Steph, we delve into the discovery of an essential fatty acid, C15:0 pentadecanoic acid, and its profound impact on health and aging! Dr. Steph shares about her journey in creating Fatty15, and how her research in the navy dolphin’s health led to the revelation that dolphins with higher levels of C15:0 experienced healthier aging, similar to humans. This odd-chain saturated fat, once overlooked due to a bias against all saturated fats, has shown to be crucial in preventing chronic inflammation, fatty liver disease, and potentially Alzheimer's disease. While the primary source of C15:0 for humans is whole dairy fat, the conversation also touches on the implications for vegans and the need for supplementation. Furthermore, C15:0's role in cellular integrity and its potential to combat various diseases, including cancer, is discussed. The interview also explores the upcoming availability of at-home C15:0 tests and the importance of maintaining adequate levels for overall health. Dr. Steph highlights the ongoing research into C15:0's benefits for brain health and its potential applications in canine longevity. The discussion concludes with an emphasis on the importance of this fatty acid, not just for humans but for our mammalian counterparts as well. You can discover more about C15:0 and the Fatty15 supplement at an DiscoverC15.com and Fatty15.com

Wednesday May 29, 2024

Biohacking and Age Reversal

Wednesday May 29, 2024

Join Dr. Sanjeev Goel and seasoned biohacker Sol-Pal John Bejarano in a deep dive into the world of biohacking. Sol-Pal shares his inspiring journey of age reversal, motivated by his father's stroke. Discover the crucial role of education, diet, supplements, and stress management in aging gracefully. Sol-Pal's approach tackles the 12 Hallmarks of Aging through a personalized regimen, offering practical tips for stress management and health optimization. Learn about Sol-Pal's meticulous tracking methods and how they enhance health without sacrificing productivity. Dive into the world of biohacking with this insightful discussion!

TIMESTAMPS:

00:00 - Intro

00:40 - Background and motivation

05:24 - Starting the biohacking journey

06:17 - Addressing genomic instability

08:01 - Managing chronic stress

11:46 - Tracking routines and staying productive

13:39 - Addressing telomere attrition

15:05 - Intro to magnesium

17:30 - Types of magnesium and dosage

20:26 - Tracking biomarkers and biological age

23:30 - Balancing diet for longevity

26:04 - Success stories in biohacking

30:01 - Functional medicine doctor recommendation

30:19 - Future of biohacking movement

32:28 - Biohacking worldwide

34:43 - Importance of coaching

35:36 - Starting your biohacking journey

37:17 - Basic supplements

41:58 - Precision supplements

42:40 - Closing remarks

Visit our website: https://peakhuman.ca

Shop here: https://peakhuman.ca/shop/

SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs

Link to Study https://jamanetwork.com/journals/jama...

📚 Purchase the Peak Longevity Prediction Pack 📚

→ https://peakhuman.ca/product/peak-lon...

📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚

→ iBooks: https://books.apple.com/ca/book/top-1...

→ Kobo: https://www.kobo.com/ca/en/ebook/the-...

→ Amazon - https://www.amazon.com/dp/B0C1J2N1YF

Friday May 17, 2024

Cardiovascular Risk Factors and Assessment

Friday May 17, 2024

Join Dr. Sanjeev Goel and Dr. Anil Maheshwari in a deep dive into cardiovascular health, discussing key risk factors, advanced lipid tests, and the importance of individualized care. Learn about cholesterol markers, genetic influences, and lifestyle modifications that can lower cardiovascular risk. Gain insights into the complexity of heart health and the latest advancements in cardiovascular care.

TIMESTAMPS:

00:00 - Intro

01:21 - Advocating for Your Health

03:45 - Ethnicity and Cardiovascular Risk

05:05 - Family History and Cardiovascular Risk

07:05 - LDL (Low-Density Lipoprotein)

10:32 - LDL Guidelines

12:51 - Oxidized LDL

14:03 - HDL (High-Density Lipoprotein)

16:33 - Total Cholesterol to HDL Ratio

19:54 - Triglycerides and Non-HDL Cholesterol

21:49 - Apolipoprotein B (APO B) and Lipoprotein A (Lp(a))

24:21 - Lipoprotein A (continued), Genetic Risk, and Medication Considerations

30:13 - High Sensitivity CRP (hs-CRP) and Inflammation

33:15 - Additional Tests and Medication Options

36:02 - Conclusion

Visit our website: https://peakhuman.ca

Shop here: https://peakhuman.ca/shop/

SUBSCRIBE TODAY: https://bit.ly/PeakHumanLabs

* Link to Study https://jamanetwork.com/journals/jama...

📚 Purchase the Peak Longevity Prediction Pack 📚

→ https://peakhuman.ca/product/peak-lon...

📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚

→ iBooks: https://books.apple.com/ca/book/top-1...

→ Kobo: https://www.kobo.com/ca/en/ebook/the-...

→ Amazon - https://www.amazon.com/dp/B0C1J2N1YF

Tuesday May 07, 2024

HRV Secrets from 'The Pulse Cure' | Optimizing Health and Performance

Tuesday May 07, 2024

Join Dr. Sanjeev Goel in discovering the transformative power of heart rate variability (HRV) with Dr. Torkil Færø as he delves into his book, "The Pulse Cure." Learn how personalized approaches and Garmin's tracking technology can optimize your HRV. Dr. Færø shares insights on improving sleep, diet, and exercise for better health. Hear success stories and explore the future of preventive medicine through HRV customization. Tune in to this episode for actionable tips on enhancing your well-being and longevity.

TIMESTAMPS:

00:00 - Intro

01:36 - Intro of Dr. Torkil Færø

03:24 - Background of Dr. Færø

05:51 - Importance of Heart Rhythm

08:35 - Tracking HRV

09:55 - New Wearable Technologies

10:51 - Aging and HRV

12:57 - Impact of Alcohol on HRV

14:48 - Success Stories

16:54 - Future Research

18:04 - Understanding Stress and Recovery