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Join Dr Sanjeev Goel, as we explore the cutting edges of medical knowledge to ”BE PEAK NOW”
Episodes
Wednesday Nov 22, 2023
Wednesday Nov 22, 2023
In this episode, Dr. Sanjeev Goel and Dr. Varun Dwaraka, Head of Bioinformatics at TruDiagnostic, discuss biologic age testing, focusing on DNA methylation and epigenetics.
They explore how epigenetic changes occur with aging, affecting gene expression. The conversation touches on the history of epigenetic clocks, aiming to predict biological age beyond chronological age. They introduce the DunedinPACE Clock, which shows promise in improving accuracy. TruDiagnostic's OM Clock integrates various data layers, providing a comprehensive aging assessment. It predicts health outcomes with higher sensitivity and specificity than existing clocks and undergoes ongoing research for response to interventions. For more details, visit www.trudiagnostic.com or connect with Dr. Varun Dwaraka on LinkedIn or Instagram.
Varun Dwaraka PhD is the Head of Bioinformatics at TruDiagnostic, and an aging and longevity investigator specializing in epigenetics and bioinformatics. He has co-authored numerous publications relating to genetics, epigenetic clocks, DNA methylation, and tissue regeneration. In 2020, Dr. Dwaraka was elected as a full member to the Sigma Xi, The Scientific Research Honor Society, and currently serves as a 2023 Foresight Fellow in Biotechnology and Health Expansion, awarded by the Foresight Institute. He also serves on the Scientific Advisory Board for SRW Labs based in New Zealand, offering insight into the application and interpretation of epigenetic age biomarkers. Dr. Dwaraka is passionate about implementing machine learning methods to advance predictive medicine, identify novel biomarkers, and create algorithms to better understand the biology of aging.
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Wednesday Nov 22, 2023
Wednesday Nov 22, 2023
In this episode, join Dr. Sanjeev Goel as he delves into the fascinating science behind amyloid beta deposition and its connection to Alzheimer's disease. Discover the historical origins of Alzheimer's research, the role of genetic mutations in amyloid buildup, and the intricate cascade of events that lead to neuroinflammation and cognitive decline.
📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚
→ iBooks: https://books.apple.com/ca/book/top-1...
→ Kobo: https://www.kobo.com/ca/en/ebook/the-...
→ Amazon - https://www.amazon.com/dp/B0C1J2N1YF
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Friday Sep 29, 2023
Friday Sep 29, 2023
Join Dr. Sanjeev Goel from Peak Human Labs and Neeraj Jain as they delve into the topic of testosterone replacement therapy. They discuss the signs of declining testosterone levels, the importance of consulting a doctor for a blood test, and the various methods of testosterone replacement, including injections and topical applications. Dr. Goel explains potential side effects and nuances to consider, emphasizing the importance of personalized medical advice. They also tease future discussions about natural ways to boost testosterone and the effectiveness of supplements like Tongkat Ali and Ashwagandha. If you found this episode helpful, don't forget to like, share, subscribe, and leave your comments. Stay tuned for more insightful content on hormone health! Continue to Be Peak!
Wednesday Sep 27, 2023
Wednesday Sep 27, 2023
Join Dr. Sanjeev Goel and Carmelia Ray as they discuss recent developments in Alzheimer's research and the aging process! Dr. Goel shares his PET scan results, revealing no amyloid deposits despite having the APOE4 allele, challenging the notion that it always leads to Alzheimer's. They also explore the dual effects of APOE4 on health, emphasizing the role of lifestyle factors in mitigating risks. This episode introduces the concept of senescence, where aging cells become dormant and contribute to inflammation and aging. They discuss potential therapies targeting senescent cells to combat aging. Be sure to like, comment, and share with a friend! Continue to Be Peak!
📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚
→ iBooks: https://books.apple.com/ca/book/top-1...
→ Kobo: https://www.kobo.com/ca/en/ebook/the-...
→ Amazon - https://www.amazon.com/dp/B0C1J2N1YF
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Monday Sep 25, 2023
Monday Sep 25, 2023
Join Dr. Sanjeev Goel and Carmelia Ray in this insightful discussion about Hormone Replacement Therapy (HRT). They talk about menopause, various ways of taking hormones, the benefits and much more. Please like, share and subscribe to our podcast!
📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚
→ iBooks: https://books.apple.com/ca/book/top-1...
→ Kobo: https://www.kobo.com/ca/en/ebook/the-...
→ Amazon - https://www.amazon.com/dp/B0C1J2N1YF
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Friday Sep 22, 2023
Friday Sep 22, 2023
Join Dr. Sanjeev Goel in an engaging conversation with Panos Papadiamantis from PNOE, a pioneer in advanced metabolic testing.
📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚
→ iBooks: https://books.apple.com/ca/book/top-1...
→ Kobo: https://www.kobo.com/ca/en/ebook/the-...
→ Amazon - https://www.amazon.com/dp/B0C1J2N1YF
******************** Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3
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Discover the science behind breath analysis and its 23 biomarkers, unveiling insights into metabolism, metabolic flexibility, and more. Learn about Zone 2 training's pivotal role in enhancing cellular fitness and how to identify your ideal intensity. Explore heart rate variability (HRV) and its impact on cardiovascular fitness and stress management, including a comparison of wearables like Whoop and Polar H10 chest strap. Dive into the importance of VO2 max for longevity and health, with PNOE Analytics paving the way for comprehensive insights in nutrition, training, and recovery programming. Don't miss this episode for practical tips on transforming your health and well-being.
****************** TIMESTAMP
0:00 - Intro
0:23 - Panos Background
1:05 - Previous Solutions for Breath Analysis
1:46 - Inspiration for Starting the Company
2:27 - Company's Holistic Approach to Breath Analysis
3:00 - Overview of the Science Behind Breath Analysis
4:08 - Biomarkers Derived from Breath Analysis
6:02 - Understanding Fat and Carbohydrate Oxidation
9:17 - The Impact of Different States on Results
11:36 - Benefits of Metabolic Flexibility
12:06 - O2/CO2 Ratios for Fat and Carbohydrate Metabolism
13:24 - Discussion on Carbohydrate Storage
13:37 - Focus on Nutrition Plans and Metabolic Flexibility
14:02 - Importance of Zone 2 Training
15:21 - Determining Zone 2 Intensity
16:01 - Explanation of Zone 2 Training
18:05 - Evaluating Heart Rate and Heart Rate Variability
21:29 - Comparing HRV Across Individuals
25:27 - The Significance of VO2 Max
27:01 - Explanation of VO2 Max and Its Importance
29:02 - Correlation Between VO2 Max and Longevity
30:31 - Factors Influencing VO2 Max
32:36 - The Impact of Exercise on VO2 Max
34:16 - The Significance of Weight Loss
35:39 - High-Intensity Interval Training (HIIT)
38:09 - Future Developments and Focus
40:00 - How to Access Pinoy Analytics Services
41:04 - Conclusion
Wednesday Sep 20, 2023
Wednesday Sep 20, 2023
In this episode, join Dr. Sanjeev Goel and Carmelia Ray where they introduce "Peak Canine," a revolutionary initiative aiming to provide human-level care for dogs. The duo discusses the inspiration behind this project, emphasizing the shift from treating ailments to focusing on preventive care for dogs. They explore innovative tests such as metabolic and genetic assessments, as well as the concept of biological age for dogs. Peak canine aims to extend dogs' lifespans and overall well-being through insights and advancements in canine care. Stay tuned for the launch of Peak K9 and a new era of comprehensive dog wellness. 🐶🐾
📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚
→ iBooks: https://books.apple.com/ca/book/top-1...
→ Kobo: https://www.kobo.com/ca/en/ebook/the-...
→ Amazon - https://www.amazon.com/dp/B0C1J2N1YF
Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3
Shop here: https://peakhuman.ca/shop/
Friday Sep 15, 2023
Friday Sep 15, 2023
Fatty liver affects about one in four individuals worldwide, yet many remain unaware of its impact. In this video, we delve into the significance of addressing this issue. Fatty liver is closely linked to conditions such as diabetes, heart disease, and obesity. Dr. Sanjeev explains the process of fatty liver development, from fat accumulation to inflammation, fibrosis, and potentially cirrhosis. The liver plays a vital role in detoxifying the body and regulating glucose, making its health paramount. Learn about the risk factors, silent progression, and the importance of regular check-ups to monitor liver enzymes. Discover lifestyle changes, including weight loss, exercise, and potential interventions like medications and vitamin E supplements. While this content aims to educate, always consult a healthcare professional for personalized advice. Support our mission to provide valuable health insights by subscribing, liking, and sharing this episode! Your support fuels our passion to create impactful content. Together, we can tackle vital health topics and make informed decisions for a better future!
📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚
→ iBooks: https://books.apple.com/ca/book/top-1...
→ Kobo: https://www.kobo.com/ca/en/ebook/the-...
→ Amazon - https://www.amazon.com/dp/B0C1J2N1YF
Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3
Shop here: https://peakhuman.ca/shop/
Wednesday Sep 13, 2023
Wednesday Sep 13, 2023
Join us as we explore what high blood pressure is, its significance, and why it's important to address. I'm taking the role of the patient this time, discussing my own experiences with high blood pressure. We cover various aspects, such as the two numbers in blood pressure readings, the factors that contribute to high blood pressure, the impacts of stress and lifestyle on blood pressure, and effective ways to manage it through diet, exercise, and even supplements like nitric oxide. We also touch on the different classes of blood pressure medications and why they might be necessary in certain cases. If you're concerned about high blood pressure or interested in optimizing your cardiovascular health, this episode is packed with valuable insights. Don't forget to like, share, and subscribe!
📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 →
iBooks: https://books.apple.com/ca/book/top-1... →
Kobo: https://www.kobo.com/ca/en/ebook/the-... →
Amazon - https://www.amazon.com/dp/B0C1J2N1YF
Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3
Shop here: https://peakhuman.ca/shop/
Monday Sep 11, 2023
Monday Sep 11, 2023
In this episode, discover the intriguing world of longevity and biohacking with Dr. Sanjeev Goel, an expert in anti-aging, to explore the potential of Metformin for extending lifespan. Should we embrace its potential benefits? We address this burning question and discuss Metformin's origin, popularity as a diabetes treatment, and its role in potentially extending lifespan. Discover how this medication, discovered in the 1920s, is now being explored beyond diabetes. We touch on the TAME trial led by Dr. Nir Barzilai, aimed at unraveling Metformin's impact on longevity. Before considering its use, remember that Metformin is a prescription medication, and expert consultation is advised. Join us at peakhuman.ca to stay updated on groundbreaking discoveries. Explore our rewards program for exclusive benefits. Tune in as we continue our quest for peak human well-being!
📚 PURCHASE DR. SANJEEV GOEL'S BOOK "The Top 10 Must Do Peak Human Biohacks of 2023"📚 →
iBooks: https://books.apple.com/ca/book/top-1... →
Kobo: https://www.kobo.com/ca/en/ebook/the-... →
Amazon - https://www.amazon.com/dp/B0C1J2N1YF
Visit our website: https://peakhuman.ca/?v=3e8d115eb4b3
Shop here: https://peakhuman.ca/shop/